Glucocorticoids Exert Direct Toxicity on Microvasculature: Analysis of Cell Death Mechanisms
نویسندگان
چکیده
منابع مشابه
Glucocorticoids induce retinal toxicity through mechanisms mainly associated with paraptosis.
PURPOSE Corticosteroids have recorded beneficial clinical effects and are widely used in medicine. In ophthalmology, besides their treatment benefits, side effects, including ocular toxicity have been observed especially when intraocular delivery is used. The mechanism of these toxic events remains, however, poorly understood. In our present study, we investigated the mechanisms and potential p...
متن کاملToxicity Mechanisms of Cigarette Smoke on Mouse Fetus Mitochondria
Maternal smoking has been recognized as a common cause of low birth weight, preterm birth and the decrease of gestational age period. Unfortunately, there is an increasing interest within public especially woman in Iran in the tobacco products consumption. On the other hand, the deleterious effect of maternal smoking on human fetus in pregnancy period especially in the first trimester encourage...
متن کاملToxicity Mechanisms of Cigarette Smoke on Mouse Fetus Mitochondria
Maternal smoking has been recognized as a common cause of low birth weight, preterm birth and the decrease of gestational age period. Unfortunately, there is an increasing interest within public especially woman in Iran in the tobacco products consumption. On the other hand, the deleterious effect of maternal smoking on human fetus in pregnancy period especially in the first trimester encourage...
متن کاملCardiac glycosides exert anticancer effects by inducing immunogenic cell death.
Some successful chemotherapeutics, notably anthracyclines and oxaliplatin, induce a type of cell stress and death that is immunogenic, hence converting the patient's dying cancer cells into a vaccine that stimulates antitumor immune responses. By means of a fluorescence microscopy platform that allows for the automated detection of the biochemical hallmarks of such a peculiar cell death modalit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2014
ISSN: 1096-0929,1096-6080
DOI: 10.1093/toxsci/kfu243